Clan CA cysteine proteases, also known as papain-like proteases, play important roles throughout the malaria parasite life cycle and are therefore potential drug targets to treat this disease and prevent its transmission.In order to study the biological function of these proteases and to chemically validate some of them as viable drug targets, high
POSISI STRATIGRAFI DAN TEKNOLOGI ALAT SERPIH SANGIRAN
Persoalan alat paleolitik dan manusia purba, masih merupakan persoalan menarik dalam hakekat sejarah perkembangan manusia.Keduanya tidak dapat dipisahkan kaitannya selama Kala Mattress Collection Plestosen, yaitu suatu periode kehidupan antara dua juta hingga 10.000 tahun silam.Oleh sifatnya yang tahan terhadap kekuatan destruktif alam, alat-alat b
Experimental Investigation of Thermal Bridges and Heat Transfer through Window Frame Elements at Achieving Energy Saving
Windows are responsible for significant Washbag amounts of energy loss through typical building envelopes.There have been multiple studies on heat loss through the glazing unit and frame system.This study presents an experimental investigation of a window unit and focuses specifically on the conductance between the structural elements and the frame
Multiple intracranial malignant melanoma metastasis: report of one case with review of literature
Objective To explore the clinicopathological and immunohistochemical features of intracranial malignant melanoma metastasis.Methods Analysed the clinical features, histopathologic findings and immunohistochemical staining in 2 lesions of one case with multiple intracranial malignant melanoma metastasis, and studied the diagnosis and differentiation
Unveiling the powerhouse: ASCL1-driven small cell lung cancer is characterized by higher numbers of mitochondria and enhanced oxidative phosphorylation
Abstract Background Small cell lung cancer (SCLC) is an aggressive malignancy with distinct molecular subtypes defined by Hayward Navigator Parts transcription factors and inflammatory characteristics.This follow-up study aimed to validate the unique metabolic phenotype in achaete-scute homologue 1 (ASCL1)-driven SCLC cell lines and human tumor tis